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Evaxion Biotech to Spearhead Development of Novel Cancer Vaccines

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Evaxion Biotech is pioneering the development of customised cancer vaccines with a targeted focus on a category of tumour antigens known as endogenous retroviruses (ERVs). These ERVs, remnants of ancient viruses lying dormant in human genomes, exhibit overexpression in cancer cells while remaining subdued in healthy tissues. The company is leveraging the power of its AI platform, AI Immunology, to identify and explore these novel cancer vaccine targets.

The AI immunology platform is instrumental in decoding the complexities of the human immune system, specifically in discovering new types of cancer vaccine targets. ERVs, being a unique class of tumour antigens, open up new avenues for precision medicine in cancer treatment. This approach is particularly promising for individuals who do not respond adequately to standard cancer immunotherapies.

Evaxion’s AI-driven technology platform provides a scalable and adaptable solution to the challenges posed by rapidly evolving pathogens and malignant cells. The platform utilizes computational modelling to swiftly detect, predict, and create vaccine candidates tailored to the specific needs of patients. This marks a significant advancement in the realm of immunotherapy, offering a customised and efficient approach to combatting diseases.

The company’s Chief Scientific Officer, Birgitte Rønø, highlighted the intensified focus on ERV cancer vaccines, aiming to streamline the development process. The goal is to deliver treatment solutions for cancer patients who have, until now, been deemed unresponsive to conventional immunotherapy approaches. The ERV cancer vaccine targets represent a breakthrough that has the potential to significantly broaden the horizons of cancer vaccine applicability.

Evaxion has already established a clinical-stage oncology pipeline for personalised vaccines and a preclinical pipeline for infectious diseases with high unmet medical needs. The preclinical activities are underway, with proof-of-concept data expected in the second half of 2024. This not only demonstrates the commitment to innovative healthcare solutions but also showcases the versatility of AI-powered approaches in addressing complex medical challenges.

The AI immunology platform, with its sophisticated prediction models, positions Evaxion at the forefront of AI-driven healthcare solutions. The company’s dedication to leveraging AI for developing immunotherapies for cancer, bacterial infections, and viral diseases underscores its commitment to advancing medical science for improved patient outcomes. The focus on ERV cancer vaccines is a testament to Evaxion’s commitment to pushing the boundaries of what is possible in cancer treatment and offering hope to individuals facing challenges with existing therapeutic options.

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